Journal: Cancer Management and Research
Article Title: Evaluation of PCR-Reverse Dot Blot Human Papillomavirus Genotyping Test in Predicting Residual/Recurrent CIN 2+ in Posttreatment Patients in China
doi: 10.2147/CMAR.S237490
Figure Lengend Snippet: The cumulative risk of residual or recurrence of CIN 2+ for postoperative patients in four4 years. ( A ) Cumulative CIN 2+ progression risk during 4 years follow-up in different age groups; ( B ) Cumulative CIN 2+ progression risk during 4 years follow-up in different HR-HPV infection numbers; ( C ) Cumulative CIN 2+ progression risk during 4 years follow-up in different margin status; ( D ) Cumulative CIN 2+ progression risk during 4 years follow-up in different gland invasive status; ( E ) Cumulative CIN 2+ progression risk during 4 years follow-up in different cytology result; ( F ) Cumulative CIN 2+ progression risk during 4 years follow-up in different pathology result; ( G ) Cumulative CIN 2+ progression risk during 4 years follow-up in different HR-HPV infection status; ( H ) Cumulative CIN 2+ progression risk during 4 years follow-up in different HR-HPV genotypes. CIN 2+ included CIN 2, CIN 3, and cervical cancer. Abbreviations: HPV, human papillomavirus; TP-HPV, type-specific HPV infection; CIN, cervical intraepithelial neoplasia; HR-HPV, high-risk human papillomavirus.
Article Snippet: In our previous study, the PCR-reverse dot blot (PCR-RDB) Yaneng ® Human Papillomavirus Genotyping Kit (Yaneng Biotech, Shenzhen, China), which detects 18 HR-HPV types (HPV-16, −18, −31, −33, −35, −39, −45, −51, −52, −53, −56, 58, −59, −66, −68, −73, −82, and −83) and 5 low-risk (LR)-HPV types (HPV-6, −11, −42, −43, and −81), was evaluated in a hospital-based population and showed a reliable and sensitive clinical reference for cervical screening.
Techniques: Infection